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With this website, you can stay in the know about how LOVENOX® helps reduce the risk of deep vein thrombosis—also known as DVT blood clots—to help avoid a potential pulmonary embolism. Learn how to self-inject LOVENOX® at home, and read about possible side effects. And get the information you need to prepare for an upcoming hospitalization, particularly if you are having total joint replacement surgery of the hip or knee.
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INDICATIONS
LOVENOX® is indicated for the prophylaxis of deep
vein thrombosis, which may lead to pulmonary embolism:
- in patients undergoing abdominal surgery who are at risk for thromboembolic complications;
- in patients undergoing hip-replacement surgery, during and following hospitalization;
- in patients undergoing knee-replacement surgery;
- in medical patients who are at risk for thromboembolic complications due to severely
restricted mobility during acute illness.
LOVENOX® injection is indicated for:
- the inpatient treatment of acute deep vein thrombosis,
with or without pulmonary embolism, when administered in conjunction with
warfarin sodium;
- the outpatient treatment of acute deep vein thrombosis,
without pulmonary embolism, when administered in conjunction with warfarin
sodium.
Important Safety Information
LOVENOX® Full Prescribing Information
Certain procedures, called "epidural/spinal anesthesia" and "spinal puncture,"
may be used as a normal part of hospitalization. Patients requiring these procedures
while being treated with LOVENOX® or
other low-molecular-weight heparins are at risk of developing a blood clot in or
around the spine. This condition may result in long-term or permanent paralysis.
LOVENOX® is not the same as "unfractionated heparin" or other drugs
called "low-molecular-weight heparins." Therefore, these drugs cannot be used interchangeably
with LOVENOX®.
LOVENOX® can alter the blood’s ability to clot. Patients treated
with LOVENOX®, who also have conditions affecting the clotting system,
must be carefully monitored by their physician. Adjusting the dose of LOVENOX®
may be necessary for patients who have certain forms of kidney disease. All patients
receiving LOVENOX®, as well as other anticoagulants, should be carefully
monitored for bleeding by their physician. Bleeding can occur at any site with LOVENOX®
use.
Platelet drops, known as "thrombocytopenia," can occur with LOVENOX®
use. Cases of a related condition called "heparin-induced thrombocytopenia" have
been observed in clinical practice. If you have had this condition, you must notify
your healthcare professional. Your physician may perform blood tests to monitor
for the occurrence of any drop in platelet count.
The use of LOVENOX® has not been adequately studied in pregnant women
with artificial (mechanical) heart valves.
LOVENOX® should not be used in patients with an allergy or sensitivity
reaction to the active ingredient called enoxaparin sodium, heparin, or pork products,
and in patients with active major bleeding.
Common side effects include mild local reactions or irritation at the site of injection,
pain, bruising, and redness of skin.
For specific questions about your health, you should always consult your physician
or a qualified healthcare professional who is responsible for your care.
Please see Full Prescribing Information including boxed
WARNING for additional important information.